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Intramolecular Cooperativity in the Reaction of Diacyl Phosphates with Serine ß-Lactamases
Asymmetric diaroyl phosphates (ArCOOPO(2)(−)OCOAr′, where Ar = Ph, Ar′ = 4-biphenyl, 2-benzothiophenyl and 2-benzofuranyl), have been prepared, evaluated as serine (classes A, C, D) β-lactamase inhibitors, and compared with respect to the latter with their symmetric “parents”, where Ar = Ar′. The as...
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885897/ https://ncbi.nlm.nih.gov/pubmed/19678666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900808x |
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