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Inhibition of Class A and C β-Lactamases by Diaroyl Phosphates

A series of diaroyl phosphates was employed to assess the general reactivity of this class of molecule against classical class A and class C β-lactamases. The compounds were found, in general, to be inhibitory substrates of both classes of enzyme. In each case, they reacted rapidly with the enzyme (...

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Detalhes bibliográficos
Main Authors: Majumdar, Sudipta, Pratt, R.F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896318/
https://ncbi.nlm.nih.gov/pubmed/19678665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900807e
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