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β(1) integrins mediate cell proliferation in three-dimensional cultures by regulating expression of the sonic hedgehog effector protein, GLI1

The β(1) integrins play an important role in the modulation of cancer cell proliferation and tumor growth. We have previously shown that β(1) integrins associate with insulin-like growth factor type 1 receptor (IGF-IR) and regulate IGF-stimulated prostate cancer cell proliferation. In the present st...

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Main Authors: Goel, Hira Lal, Underwood, Jean M., Nickerson, Jeffrey A., Hsieh, Chung-Cheng, Languino, Lucia R.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885855/
https://ncbi.nlm.nih.gov/pubmed/20333644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22116
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