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Gli1 Mediates Lung Cancer Cell Proliferation and Sonic Hedgehog-Dependent Mesenchymal Cell Activation

Non-Small-Cell-Lung-Cancer (NSCLC) represents approximately 85% of all lung cancers and remains poorly understood. While signaling pathways operative during organ development, including Sonic Hedgehog (Shh) and associated Gli transcription factors (Gli1-3), have recently been found to be reactivated...

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Detalhes bibliográficos
Main Authors: Bermudez, Olga, Hennen, Elisabeth, Koch, Ina, Lindner, Michael, Eickelberg, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646741/
https://ncbi.nlm.nih.gov/pubmed/23667589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063226
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