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A Randomized Phase I Study of Testosterone Replacement for Patients with Low Risk Castrate Resistant Prostate Cancer

BACKGROUND: The androgen pathway remains biologically relevant even in castration resistant prostate cancer (CRPC). In preclinical models, androgen therapy for CRPC leads to growth arrest, apoptosis, and tumor shrinkage. This study determined the toxicity and feasibility of a testosterone therapy in...

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Detalhes bibliográficos
Main Authors: Szmulewitz, Russell, Mohile, Supriya, Posadas, Edwin, Karrison, Rangesh Kunnavakkam Theodore, Manchen, Elizabeth, Stadler, Walter M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885777/
https://ncbi.nlm.nih.gov/pubmed/19282098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2009.02.022
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