Prospective International Randomized Phase II Study of Low-Dose Abiraterone With Food Versus Standard Dose Abiraterone In Castration-Resistant Prostate Cancer

PURPOSE: Abiraterone acetate (AA) is a standard of care for metastatic castration-resistant prostate cancer (CRPC). Despite a large food effect, AA was administered under fasting conditions in its pivotal trials. We sought to test the hypothesis that low-dose AA (LOW; 250 mg with a low-fat meal) wou...

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Vydáno v:J Clin Oncol
Hlavní autoři: Szmulewitz, Russell Z., Peer, Cody J., Ibraheem, Abiola, Martinez, Elia, Kozloff, Mark F., Carthon, Bradley, Harvey, R. Donald, Fishkin, Paul, Yong, Wei Peng, Chiong, Edmund, Nabhan, Chadi, Karrison, Theodore, Figg, William D., Stadler, Walter M., Ratain, Mark J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Clinical Oncology 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5941614/
https://ncbi.nlm.nih.gov/pubmed/29590007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2017.76.4381
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