Functional and structural studies of the vaccinia virus virulence factor N1 reveal a Bcl-2-like anti-apoptotic protein

Vaccinia virus (VACV) encodes many immunomodulatory proteins, including inhibitors of apoptosis and modulators of innate immune signalling. VACV protein N1 is an intracellular homodimer that contributes to virus virulence and was reported to inhibit nuclear factor (NF)-κB signalling. However, analys...

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Detalhes bibliográficos
Main Authors: Cooray, Samantha, Bahar, Mohammad W., Abrescia, Nicola G. A., McVey, Colin E., Bartlett, Nathan W., Chen, Ron A.-J., Stuart, David I., Grimes, Jonathan M., Smith, Geoffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for General Microbiology 2007
Assuntos:
Jgv Direct
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885619/
https://ncbi.nlm.nih.gov/pubmed/17485524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.82772-0
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