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Comparison of current docking tools for the simulation of inhibitor binding by the transmembrane domain of the sarco/endoplasmic reticulum calcium ATPase

Inhibitors of the transmembrane protein sarco/endoplasmic reticulum calcium ATPase (SERCA) are invaluable tools for the study of the enzyme’s physiological functions and they have been recognized as a promising new class of anticancer agents. For the discovery of novel enzyme inhibitors, small molec...

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Detalhes bibliográficos
Main Authors: Lape, Michael, Elam, Christopher, Paula, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885586/
https://ncbi.nlm.nih.gov/pubmed/20167416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2010.01.011
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