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Thermodynamics of cation binding to the sarco/endoplasmic reticulum calcium ATPase pump and impacts on enzyme function
Sarcoendoplasmic reticulum Ca(2+)-ATPase (SERCA) is a transmembrane pump that plays an important role in transporting calcium into the sarcoplasmic reticulum (SR). While calcium (Ca(2+)) binds SERCA with micromolar affinity, magnesium (Mg(2+)) and potassium (K(+)) also compete with calcium (Ca(2+))...
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| Veröffentlicht in: | J Chem Theory Comput |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7336277/ https://ncbi.nlm.nih.gov/pubmed/30807147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.8b01312 |
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