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Effects of branching architecture and linker on the activity of hyperbranched polymer-drug conjugates

Drug release from hyperbranched polymer-drug conjugates and the subsequent activity are influenced by the branching architecture and the linker. To gain an understanding of these effects, we used hyperbranched polyol and G4-OH Polyamidoamine (PAMAM) dendrimer with methyl prednisolone (MP) as the mod...

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書誌詳細
主要な著者: Perumal, Omathanu, Khandare, Jayant, Kolhe, Parag, Kannan, Sujatha, Lieh-Lai, Mary, Kannan, Rangaramanujam M.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885566/
https://ncbi.nlm.nih.gov/pubmed/19402625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc800526z
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