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Dendrimers-drug conjugates for tailored intracellular drug release based on glutathione levels

N-Acetyl-L-Cysteine (NAC) is an anti-oxidant and anti-inflammatory agent with significant potential in clinical applications including stroke and neuroinflammation. The drug shows high plasma binding upon IV administration, requiring high doses and associated side effects. Through the use of an appr...

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Detalhes bibliográficos
Main Authors: Navath, Raghavendra S., Kurtoglu, Yunus E., Wang, Bing, Kannan, Sujatha, Romero, Robert, Kannan, Rangaramanujam M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727757/
https://ncbi.nlm.nih.gov/pubmed/19053299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc800342d
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