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Poly(amidoamine) Dendrimer-Drug Conjugates with Disulfide Linkages for Intracellular Drug Delivery

Understanding and improving drug release kinetics from dendrimer-drug conjugates is a key step to improving their in vivo efficacy. N-Acetylcysteine (NAC) is an anti-inflammatory agent with significant potential for clinical use in the treatment of neuroinflammation, stroke and cerebral palsy. There...

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Detalles Bibliográficos
Main Authors: Kurtoglu, Yunus E., Navath, Raghavendra S., Wang, Bing, Kannan, Sujatha, Romero, Robert, Kannan, Rangaramanujam M.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692182/
https://ncbi.nlm.nih.gov/pubmed/19171376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2008.12.054
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