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The Absence of Serum IgM Enhances the Susceptibility of Mice to Pulmonary Challenge with Cryptococcus neoformans

The importance of T cell-mediated immunity for resistance to the disease (cryptococcal disease) caused by Cryptococcus neoformans is incontrovertible, but whether Ab immunity also contributes to resistance remains uncertain. To investigate the role of IgM in resistance to C. neoformans, we compared...

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Autores principales: Subramaniam, Krishanthi S., Datta, Kausik, Quintero, Eric, Manix, Catherine, Marks, Matthew S., Pirofski, Liise-anne
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885446/
https://ncbi.nlm.nih.gov/pubmed/20404271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901638
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