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Human IgM Inhibits the Formation of Titan-Like Cells in Cryptococcus neoformans

Human studies have shown associations between cryptococcal meningitis and reduced IgM memory B cell levels, and studies in IgM- and/or B cell-deficient mice have demonstrated increased Cryptococcus neoformans dissemination from lungs to brain. Since immunoglobulins are part of the immune milieu that...

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Foilsithe in:Infect Immun
Main Authors: Trevijano-Contador, Nuria, Pianalto, Kaila M., Nichols, Connie B., Zaragoza, Oscar, Alspaugh, J. Andrew, Pirofski, Liise-anne
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093138/
https://ncbi.nlm.nih.gov/pubmed/31988178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00046-20
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