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Genome-wide estimation of firing efficiencies of origins of DNA replication from time-course copy number variation data

BACKGROUND: DNA replication is a fundamental biological process during S phase of cell division. It is initiated from several hundreds of origins along whole chromosome with different firing efficiencies (or frequency of usage). Direct measurement of origin firing efficiency by techniques such as DN...

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Detalhes bibliográficos
Main Authors: Luo, Huaien, Li, Juntao, Eshaghi, Majid, Liu, Jianhua, Karuturi, R Krishna Murthy
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885374/
https://ncbi.nlm.nih.gov/pubmed/20462459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-247
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