Novel origins of copy number variation in the dog genome

BACKGROUND: Copy number variants (CNVs) account for substantial variation between genomes and are a major source of normal and pathogenic phenotypic differences. The dog is an ideal model to investigate mutational mechanisms that generate CNVs as its genome lacks a functional ortholog of the PRDM9 g...

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Bibliografiska uppgifter
Huvudupphovsmän: Berglund, Jonas, Nevalainen, Elisa M, Molin, Anna-Maja, Perloski, Michele, André, Catherine, Zody, Michael C, Sharpe, Ted, Hitte, Christophe, Lindblad-Toh, Kerstin, Lohi, Hannes, Webster, Matthew T
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2012
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053742/
https://ncbi.nlm.nih.gov/pubmed/22916802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-8-r73
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