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A Microhomology-Mediated Break-Induced Replication Model for the Origin of Human Copy Number Variation
Chromosome structural changes with nonrecurrent endpoints associated with genomic disorders offer windows into the mechanism of origin of copy number variation (CNV). A recent report of nonrecurrent duplications associated with Pelizaeus-Merzbacher disease identified three distinctive characteristic...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2621351/ https://ncbi.nlm.nih.gov/pubmed/19180184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000327 |
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