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Mechanisms of change in gene copy number

Deletions and duplications of chromosomal segments (copy-number variations or CNVs) constitute a major source of variation between individual humans, underlying human evolution and many diseases from mental illness and developmental disorders to cancer. CNVs form at rates far outstripping other kind...

詳細記述

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書誌詳細
主要な著者: Hastings, PJ, Lupski, James R, Rosenberg, Susan M, Ira, Grzegorz
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864001/
https://ncbi.nlm.nih.gov/pubmed/19597530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg2593
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