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Analysis of substructural variation in families of enzymatic proteins with applications to protein function prediction

BACKGROUND: Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the structure and chemistry of the catalytic binding site residues can be loosely defined as a substructure of the protein. Compar...

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Detalhes bibliográficos
Main Authors: Bryant, Drew H, Moll, Mark, Chen, Brian Y, Fofanov, Viacheslav Y, Kavraki, Lydia E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885373/
https://ncbi.nlm.nih.gov/pubmed/20459833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-242
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