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The effects of the mGluR5 receptor antagonist 6-methyl-2-(phenylethynyl)-pyridine (MPEP) on behavioural responses to nicotine

RATIONALE: Previous studies have shown that blockade of metabotropic glutamate 5 receptors (mGluR5) results in inhibition of nicotine self-administration in experimental animals. However, these studies have not established the behavioural mechanisms which mediate these effects or the extent to which...

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Autori principali: Tronci, Valeria, Vronskaya, Svetlana, Montgomery, Nicholas, Mura, Daniela, Balfour, David J. K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885299/
https://ncbi.nlm.nih.gov/pubmed/20422403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-010-1868-x
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