Long dsRNA induces an antiviral response independent of IRF3, IPS-1 and IFN

Virus infection elicits a robust innate antiviral response dominated by the production of type 1 IFN. In non-professional innate immune cells such as fibroblasts, type 1 IFN is rapidly produced following the recognition of viral dsRNA and the subsequent activation of the constitutively expressed tra...

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Hauptverfasser: DeWitte-Orr, Stephanie J., Mehta, Devangi R., Collins, Susan E., Suthar, Mehul, Gale, Michael, Mossman, Karen L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885285/
https://ncbi.nlm.nih.gov/pubmed/19864603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900867
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