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Understanding Viral dsRNA-Mediated Innate Immune Responses at the Cellular Level Using a Rainbow Trout Model

Viruses across genome types produce long dsRNA molecules during replication [viral (v-) dsRNA]. dsRNA is a potent signaling molecule and inducer of type I interferon (IFN), leading to the production of interferon-stimulated genes (ISGs), and a protective antiviral state within the cell. Research on...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Poynter, Sarah J., DeWitte-Orr, Stephanie J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924774/
https://ncbi.nlm.nih.gov/pubmed/29740439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00829
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