Enhancing innate antiviral immune responses in rainbow trout by double stranded RNA delivered with cationic phytoglycogen nanoparticles

Innate immunity is induced when pathogen-associated molecular patterns (PAMPs) bind host pattern recognition receptors (PRRs). Polyinosinic:polycytidylic acid [poly(I:C)] is a synthetic analogue of viral dsRNA that acts as a PAMP, inducing type I interferons (IFNs) in vertebrates. In the present stu...

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Publicat a:Sci Rep
Autors principals: Alkie, Tamiru N., de Jong, Jondavid, Jenik, Kristof, Klinger, Karl M., DeWitte-Orr, Stephanie J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754369/
https://ncbi.nlm.nih.gov/pubmed/31541160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49931-2
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