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Peroxisome Proliferator-activated Receptor γ Coactivator 1α or 1β Overexpression Inhibits Muscle Protein Degradation, Induction of Ubiquitin Ligases, and Disuse Atrophy
Overexpression of the transcriptional coactivator peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α), like exercise, increases mitochondrial content and inhibits muscle atrophy. To understand these actions, we tested whether PGC-1α or its close homolog, PGC-1β, influences muscle pr...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885225/ https://ncbi.nlm.nih.gov/pubmed/20404331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.113092 |
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