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HLA-DR-restricted T-cell responses to Factor VIII epitopes in a mild haemophilia A family with missense substitution A2201P
INTRODUCTION: An HLA-DRA-DRB1*0101-restricted T-cell epitope in the factor VIII (FVIII) C2 domain occurred in a mild haemophilia A patient with missense substitution FVIII-A2201P. His T cells responded to synthetic peptides FVIII(2186-2205) and FVIII(2194-2213). AIM: T cells from family members with...
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Asıl Yazarlar: | , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
2010
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885051/ https://ncbi.nlm.nih.gov/pubmed/20536985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2516.2008.01905.x |
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