Options for Inactivation, Adjuvant, and Route of Topical Administration of a Killed, Unencapsulated Pneumococcal Whole-Cell Vaccine

We previously reported that ethanol-killed cells of a noncapsulated strain of Streptococcus pneumoniae, given intranasally with cholera toxin as an adjuvant, protect rats against pneumonia and mice against colonization of the nasopharynx and middle ear by capsulated pneumococci of various serotypes....

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Detalhes bibliográficos
Main Authors: Lu, Ying-Jie, Yadav, Puja, Clements, John D., Forte, Sophie, Srivastava, Amit, Thompson, Claudette M., Seid, Robert, Look, Jee, Alderson, Mark, Tate, Andrea, Maisonneuve, Jean-François, Robertson, George, Anderson, Porter W., Malley, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Vaccine Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884428/
https://ncbi.nlm.nih.gov/pubmed/20427625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00036-10
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