Vaccination of Rabbits with an Alkylated Toxoid Rapidly Elicits Potent Neutralizing Antibodies against Botulinum Neurotoxin Serotype B

New Zealand White (NZW) rabbits were immunized with several different nontoxic botulinum neurotoxin serotype B (BoNT/B) preparations in an effort to optimize the production of a rapid and highly potent, effective neutralizing antibody response. The immunogens included a recombinant heavy chain (rHc)...

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Bibliografske podrobnosti
Main Authors: Held, Daniel M., Shurtleff, Amy C., Fields, Scott, Green, Christopher, Fong, Julie, Jones, Russell G. A., Sesardic, Dorothea, Buelow, Roland, Burke, Rae Lyn
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Vaccine Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884417/
https://ncbi.nlm.nih.gov/pubmed/20410329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00493-09
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