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Anergic T Cells Are Metabolically Anergic
Full T cell activation requires TCR engagement (signal 1) in the context of costimulation (signal 2). Costimulation is required for maximal expression of effector cytokines and prevention of T cell anergy. It has become increasingly clear that another major function of costimulation is to up-regulat...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2884282/ https://ncbi.nlm.nih.gov/pubmed/19841171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803510 |
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