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CREB is a key regulator of striatal vulnerability in chemical and genetic models of Huntington’s Disease
Evidence of dysregulation of the CREB/CRE transcriptional pathway in animal models of Huntington’s disease (HD) suggests that strategies designed to augment CRE-mediated transcription may be of therapeutic value. Here, we investigated the consequences of CREB activation and repression in chemical an...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2884277/ https://ncbi.nlm.nih.gov/pubmed/19632326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2009.07.014 |
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