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CREB is a key regulator of striatal vulnerability in chemical and genetic models of Huntington’s Disease

Evidence of dysregulation of the CREB/CRE transcriptional pathway in animal models of Huntington’s disease (HD) suggests that strategies designed to augment CRE-mediated transcription may be of therapeutic value. Here, we investigated the consequences of CREB activation and repression in chemical an...

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Detalhes bibliográficos
Main Authors: Choi, Yun-Sik, Lee, Boyoung, Cho, Hee-Yeon, Reyes, Iza B., Pu, Xin-An, Saido, Takaomi C., Hoyt, Kari R., Obrietan, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884277/
https://ncbi.nlm.nih.gov/pubmed/19632326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2009.07.014
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