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An Electrostatic Model for DNA Surface Hybridization
DNA hybridization at surfaces is a crucial process for biomolecular detection, genotyping, and gene expression analysis. However, hybridization density and kinetics can be strongly inhibited by electric fields from the negatively charged DNA as the reaction proceeds. Here, we develop an electrostati...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Biophysical Society
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2884251/ https://ncbi.nlm.nih.gov/pubmed/20550908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.03.017 |
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