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Probing the Electrostatic Shielding of DNA with Capillary Electrophoresis

The free solution mobility of a 20-bp double-stranded DNA oligomer has been measured in diethylmalonate (DM) and Tris-acetate buffers, with and without added NaCl or TrisCl. DM buffers have the advantage that the buffering ion is anionic, so the cation composition in the solution can be varied at wi...

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Bibliographic Details
Main Authors: Stellwagen, Earle, Stellwagen, Nancy C.
Format: Artigo
Language:Inglês
Published: Biophysical Society 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302754/
https://ncbi.nlm.nih.gov/pubmed/12609887
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