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Down-State Model of the Voltage-Sensing Domain of a Potassium Channel
Voltage-sensing domains (VSDs) of voltage-gated potassium (Kv) channels undergo a series of conformational changes upon membrane depolarization, from a down state when the channel is at rest to an up state, all of which lead to the opening of the channel pore. The crystal structures reported to date...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2884232/ https://ncbi.nlm.nih.gov/pubmed/20550898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.03.031 |
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