Down-State Model of the Voltage-Sensing Domain of a Potassium Channel

Voltage-sensing domains (VSDs) of voltage-gated potassium (Kv) channels undergo a series of conformational changes upon membrane depolarization, from a down state when the channel is at rest to an up state, all of which lead to the opening of the channel pore. The crystal structures reported to date...

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Detaylı Bibliyografya
Asıl Yazarlar: Schow, Eric V., Freites, J. Alfredo, Gogna, Karun, White, Stephen H., Tobias, Douglas J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Biophysical Society 2010
Konular:
Channels and Transporters
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884232/
https://ncbi.nlm.nih.gov/pubmed/20550898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.03.031
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