Atomistic Modeling of Ion Conduction through the Voltage-Sensing Domain of the Shaker K(+) Ion Channel

Voltage-sensing domains (VSDs) sense changes in the membrane electrostatic potential and, through conformational changes, regulate a specific function. The VSDs of wild-type voltage-dependent K(+), Na(+), and Ca(2+) channels do not conduct ions, but they can become ion-permeable through pathological...

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Udgivet i:J Phys Chem B
Main Authors: Wood, Mona L., Freites, J. Alfredo, Tombola, Francesco, Tobias, Douglas J.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605276/
https://ncbi.nlm.nih.gov/pubmed/28074656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.6b12639
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