GLOBAL TARGETING OF SUBCELLULAR Hsp90 NETWORKS FOR THERAPY OF GLIOBLASTOMA*

Drug discovery for complex and heterogeneous tumors now aims at dismantling global networks of disease maintenance, but the subcellular requirements of this approach are not understood. Here, we simultaneously targeted the multiple subcellular compartments of the molecular chaperone Heat Shock Prote...

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Main Authors: Siegelin, Markus D., Plescia, Janet, Raskett, Christopher M., Gilbert, Candace A., Ross, Alonzo H., Altieri, Dario C.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884083/
https://ncbi.nlm.nih.gov/pubmed/20501802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0097
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