The role of organic anion-transporting polypeptides and their common genetic variants in mycophenolic acid pharmacokinetics

The goal of this study was to determine the role of the Organic Anion Transporting Polypeptides, OATP1A2, OATP1B1 and OATP1B3 and their genetic variants in the pharmacokinetics of the immunosuppressive drug mycophenolate mofetil (MMF). Using OATP-transfected HEK cells, we measured the uptake of myco...

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Autori principali: Picard, Nicolas, Yee, Sook Wah, Woillard, J. B., Lebranchu, Yvon, Le Meur, Yannick, Giacomini, Kathleen M., Marquet, Pierre
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Pub. Group 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884029/
https://ncbi.nlm.nih.gov/pubmed/19890249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2009.205
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