Positive Charges of Translocating Polypeptide Chain Retrieve an Upstream Marginal Hydrophobic Segment from the Endoplasmic Reticulum Lumen to the Translocon

Positively charged amino acid residues are well recognized topology determinants of membrane proteins. They contribute to the stop-translocation of a polypeptide translocating through the translocon and to determine the orientation of signal sequences penetrating the membrane. Here we analyzed the f...

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Hlavní autoři: Fujita, Hidenobu, Kida, Yuichiro, Hagiwara, Masatoshi, Morimoto, Fumiko, Sakaguchi, Masao
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883948/
https://ncbi.nlm.nih.gov/pubmed/20427573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-12-1060
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