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A mathematical model of hepatitis c virus dynamics in patients with high baseline viral loads or advanced liver disease

BACKGROUND & AIMS: Patients with baseline hepatitis C virus-RNA levels (bHCV-RNA) >6 log IU/ml or cirrhosis have a reduced probability of a sustained-virological response (SVR). We examined the relationship between bHCV-RNA, cirrhosis and SVR using a mathematical model that includes the criti...

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Autors principals: Dahari, Harel, Layden-Almer, Jennifer E., Kallwitz, Eric, Ribeiro, Ruy M., Cotler, Scott J., Layden, Thomas J., Perelson, Alan S.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883911/
https://ncbi.nlm.nih.gov/pubmed/19208338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.12.060
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