Upregulation of the apelin–APJ pathway promotes neointima formation in the carotid ligation model in mouse

AIMS: To investigate apelin–APJ (angiotensin receptor- like 1) signalling in vascular remodelling, we have examined the pathophysiological response to carotid ligation in apelin knockout mice. METHODS AND RESULTS: Apelin null animals compared with wild-type mice had significantly decreased neointima...

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Main Authors: Kojima, Yoko, Kundu, Ramendra K., Cox, Christopher M., Leeper, Nicholas J., Anderson, Joshua A., Chun, Hyung J., Ali, Ziad A., Ashley, Euan A., Krieg, Paul A., Quertermous, Thomas
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883899/
https://ncbi.nlm.nih.gov/pubmed/20176814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq052
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