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Chemoselective Protection of α-Ketoacids by Direct Annulations with Oximes

[Image: see text] Oximes and α-ketoacids undergo an unexpectedly facile and chemoselective annulation to afford 2,5-dihydrooxazole 3-oxides. The resulting cyclic nitrones serve as chemically and configurationally stable masked α-ketoacids that can be easily elaborated and manipulated. Deprotection i...

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Detaylı Bibliyografya
Asıl Yazarlar: Flores, Melissa A., Bode, Jeffrey W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883889/
https://ncbi.nlm.nih.gov/pubmed/20356071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol100467t
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