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Dichloroacetate induces apoptosis and cell-cycle arrest in colorectal cancer cells
BACKGROUND: Cancer cells are highly dependent on glycolysis. Our aim was to determine if switching metabolism from glycolysis towards mitochondrial respiration would reduce growth preferentially in colorectal cancer cells over normal cells, and to examine the underlying mechanisms. METHODS: Represen...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2883702/ https://ncbi.nlm.nih.gov/pubmed/20485289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605701 |
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