BRAF mutations, microsatellite instability status and cyclin D1 expression predict metastatic colorectal patients’ outcome

BACKGROUND: The significance of BRAF mutations, microsatelite instability (MSI) status and cyclin D1 expression in patients with metastatic colorectal cancer (mCRC) was evaluated. METHODS: Primary tumours from 144 patients treated for mCRC were assessed for BRAF (V600E) mutation, MSI status and cycl...

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Bibliographische Detailangaben
Hauptverfasser: Saridaki, Z, Papadatos-Pastos, D, Tzardi, M, Mavroudis, D, Bairaktari, E, Arvanity, H, Stathopoulos, E, Georgoulias, V, Souglakos, J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
Schlagworte:
Molecular Diagnostics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883698/
https://ncbi.nlm.nih.gov/pubmed/20485284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605694
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