Pregnane X receptor suppresses proliferation and tumourigenicity of colon cancer cells

BACKGROUND: Pregnane X receptor (PXR) is a nuclear receptor that regulates the metabolism and disposition of various xenobiotics and endobioitics. We investigated a novel PXR function in regulating colon tumourigenesis in this study. METHODS: Histochemistry, transfection, cell proliferation assay, a...

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Detalhes bibliográficos
Main Authors: Ouyang, N, Ke, S, Eagleton, N, Xie, Y, Chen, G, Laffins, B, Yao, H, Zhou, B, Tian, Y
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883694/
https://ncbi.nlm.nih.gov/pubmed/20531417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605677
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