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The Antiapoptotic Role of Pregnane X Receptor in Human Colon Cancer Cells
The orphan nuclear receptor pregnane X receptor (PXR) plays an important role in the detoxification of foreign and endogenous chemicals, including bile acids. PXR promotes bile acid elimination by activating bile acid-detoxifying enzymes and transporters. Certain bile acids are known to promote colo...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Endocrine Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2276464/ https://ncbi.nlm.nih.gov/pubmed/18096695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0197 |
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