Self-Protection against Gliotoxin—A Component of the Gliotoxin Biosynthetic Cluster, GliT, Completely Protects Aspergillus fumigatus Against Exogenous Gliotoxin

Gliotoxin, and other related molecules, are encoded by multi-gene clusters and biosynthesized by fungi using non-ribosomal biosynthetic mechanisms. Almost universally described in terms of its toxicity towards mammalian cells, gliotoxin has come to be considered as a component of the virulence arsen...

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Bibliographic Details
Main Authors: Schrettl, Markus, Carberry, Stephen, Kavanagh, Kevin, Haas, Hubertus, Jones, Gary W., O'Brien, Jennifer, Nolan, Aine, Stephens, John, Fenelon, Orla, Doyle, Sean
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883607/
https://ncbi.nlm.nih.gov/pubmed/20548963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000952
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