Gliotoxin Is a Virulence Factor of Aspergillus fumigatus: gliP Deletion Attenuates Virulence in Mice Immunosuppressed with Hydrocortisone

Gliotoxin is an immunosuppressive mycotoxin long suspected to be a potential virulence factor of Aspergillus fumigatus. Recent studies using mutants lacking gliotoxin production, however, suggested that the mycotoxin is not important for pathogenesis of A. fumigatus in neutropenic mice resulting fro...

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Detalhes bibliográficos
Main Authors: Sugui, Janyce A., Pardo, Julian, Chang, Yun C., Zarember, Kol A., Nardone, Glenn, Galvez, Eva M., Müllbacher, Arno, Gallin, John I., Simon, Markus M., Kwon-Chung, Kyung J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043361/
https://ncbi.nlm.nih.gov/pubmed/17601876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00141-07
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