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Employing Information Theoretic Measures and Mutagenesis to Identify Residues Critical for Drug-Proton Antiport Function in Mdr1p of Candida albicans

By employing information theoretic measures, this study presents a structure and functional analysis of a multidrug-proton antiporter Mdr1p of Candida albicans. Since CaMdr1p belongs to drug-proton antiporter (DHA1) family of Major Facilitator Superfamily (MFS) of transporters, we contrasted DHA1 (a...

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Detalhes bibliográficos
Main Authors: Kapoor, Khyati, Rehan, Mohd, Lynn, Andrew M., Prasad, Rajendra
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883579/
https://ncbi.nlm.nih.gov/pubmed/20548793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011041
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