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SHP-1 deficiency and increased inflammatory gene expression in PBMCs of multiple sclerosis patients
Recent studies in mice have demonstrated that the protein tyrosine phosphatase SHP-1 is a crucial negative regulator of cytokine signaling, inflammatory gene expression, and demyelination in central nervous system. The present study investigates a possible similar role for SHP-1 in the human disease...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2883308/ https://ncbi.nlm.nih.gov/pubmed/18209728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.3700720 |
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