Physiological and genetic analyses of inbred mouse strains with a type I iodothyronine 5' deiodinase deficiency.

Inbred mouse strains differ in their capacity to deiodinate iododioxin and iodothyronines, with strains segregating into high or low activity groups. Metabolism of iododioxin occurs via the type I iodothyronine 5'deiodinase (5'DI), one of two enzymes that metabolize thyroxine (T4) to 3,5,3'-triiodot...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Berry, M J, Grieco, D, Taylor, B A, Maia, A L, Kieffer, J D, Beamer, W, Glover, E, Poland, A, Larsen, P R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288298/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8104199/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116730
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